Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America. Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan. Suburban Hospital, Bethesda, Maryland, United States of America. Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Moran Center for Translational Medicine, John A. Moran Eye Center, Department of Ophthalmology & Visual Sciences, University of Utah School of Medicine, Salt Lake City, Utah, United States of America; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America; Schepens Eye Research Institute, Boston, Massachusetts, United States of America.